The advancement in the field of immunotherapeutics has led to a new drive to comprehend the tumor microenvironment. Immunohistochemistry is a robust tool for the investigation of the expression, ...

To be adopted in the routine clinical setting, a biomarker must both demonstrate a clear additional benefit over standard clinical, radiological, and pathological examination (usually to predict ...

Immunohistochemistry plays a key role in the diagnosis of soft tissue tumors. Until recently, however, the primary purpose of immunohistochemistry in this context was simply to attempt to demonstrate ...

Immunohistochemistry (IHC) is a newer technique for assessing the estrogen receptor (ER) status of breast cancers, with the potential to overcome many of the shortcomings associated with the ...

In immunohistochemistry, colored substrates are used to detect specific proteins within a biological sample. For example, after application of the primary antibody, a second antibody conjugated to an ...

A new study evaluates immunohistochemistry-based subtype classification of breast tumors for the prediction of disease outcome. A study by Paul Pharoah and colleagues published in this week's PLoS ...

Immunohistochemistry (IHC) has continually evolved alongside technological and scientific advances. Because scientists constantly develop and modify their IHC techniques to better answer modern ...

Researchers from Lund University (Sweden) have investigated the tumor immune microenvironment of primary triple-negative breast cancer using digital image analysis of IHC-stained immune cells. To do ...

Personalized medicine depends on tools, such as immunohistochemistry (IHC), that identify precise targets in a patient’s disease. Immunohistochemistry (IHC) staining is integral in developing ...

The development of many different chromogens for light microscopy gives us the opportunity to explore different usage of multiplex immunohistochemistry (IHC) for clinical diagnostic purposes as well ...