Viruses are small obligate intracellular parasites with either a RNA or DNA genome that are surrounded by a protective protein coat and transfer their genetic material to infected cells. Lentivirus ...

Thorough lentivirus characterization is essential for generating the highest quality gene therapy. Traditional methods only look at one piece of the puzzle, require purified samples, and can take days ...

Metachromatic leukodystrophy (MLD) is a rare genetic disorder caused by the deficiency of arylsulfatase A (ARSA) or its activator prosaposin (PSAP). This leads to the accumulation of sulfatides in the ...

In spite of advances in conventional four-plasmid transient transfection methods and development of inducible stable production cell lines, production of replication-defective lentiviral vectors in ...

To initiate a lentivirus service, we recommend that you contact us to discuss creation of your lentivirus vector. We can discuss which transfer plasmid is most suited for your application and can ...

Lentivirus is a genus in the family of Retroviridae that is very suitable for remodeling into gene transfer vectors due to its stable transgene expression, the ability to reach the nuclei of the ...

Research led by Christian Medical College in Vellore, India, has demonstrated the successful use of lentiviral vectors to deliver gene therapy for patients with severe hemophilia A. The study presents ...

Lentiviruses have the unique ability amongst retroviruses of being able to infect non-cycling cells. Vectors derived from lentiviruses have provided a huge advancement in technology and seemingly ...

Lentiviral transduction is a popular delivery platform for applications such as CAR-T cell engineering or CRISPR-Cas9 gene editing, as it can transduce both dividing and non-dividing cells and ...

During the virtual Bioprocessing Summit in August, Cytiva reported that its new filtration process has advantages compared to traditional centrifuge approaches for removing viruses from suspension ...