Mood stabilizers protect against suicide and all-cause mortality in patients with bipolar disorder (BD), including natural mortality, with lithium emerging as the most protective agent, new research ...

Recent lithium and valproate use was associated with a 34%-46% lower risk for suicide in patients with schizophrenia or bipolar disorder (BD), investigators leading a large cohort study reported.

Long-term mood stabilizer use in bipolar disorder Mixed and psychotic features and comorbid anxiety disorder were also associated with poor treatment response. About one-third of patients receiving ...

A study this week in the journal Nature found that the loss of lithium, a naturally occurring element in the brain, could be an early sign of Alzheimer’s and a powerful driver of the disease, which ...

Rapid cycling can be confusing when mood shifts do not follow neat diagnostic lines. The first goal is mood stability — ...

A second meta-analysis of antimanic treatments, conducted by Yildiz et al, 6 focused on direct comparisons of individual medications and on effects of classes of medication. Second-generation ...

Lithium was associated with a higher risk of thyroid and kidney dysfunction versus non-lithium treatments in bipolar disorder patients. Associations were dose-dependent and serum level cutoffs for ...