New research suggests pain is not a simple signal of injury but a process that unfolds across nerves, spinal cord, and brain.

All over the body are tiny sensors called nociceptors whose job is to spot potentially harmful stimuli and send warning ...

Four tiny 3D organs connected themselves in a lab dish, forming a replica of the human pain pathway, in a new study. The discovery allows scientists to better understand chronic pain and how pain ...

Researchers at UC Santa Barbara identified a pain pathway in fruit flies that reduces the sensation of pain from heat. The researchers discovered that just a single neuron on each side of the animal’s ...

Stanford Medicine investigators have replicated, in a lab dish, one of the most prominent human nervous pathways for sensing pain. This nerve circuit transmits sensations from the body’s skin to the ...

Pain management is a tricky area for physicians: they don’t want patients suffering, but current treatment options are limited, with highly addictive opioids one of the few available resources.

Pain, often rated as the most significant symptom of hidradenitis suppurativa (HS), can substantially reduce quality of life and increase the risk of disability and chronic opioid use. Although the ...