Nonalcoholic fatty liver disease (NAFLD) is a prevalent metabolic disorder with a complex pathogenesis. Although epitranscriptomic modifications such as N6-methyladenosine (m6A) have been implicated ...

A new review brings attention to the STING pathway as a critical regulator in both colitis and colon cancer, highlighting its complex and often opposing roles in inflammation and tumor development.

A new review article highlights the expanding importance of glutamine metabolism in shaping the tumor microenvironment, offering fresh perspectives on how metabolic interactions influence cancer progr ...

A new wave of scientific understanding is placing ferroptosis, a distinct form of iron-dependent cell death, at the forefront of efforts to overcome drug resistance in digestive cancers. These cancers ...

Transverse aortic constriction (TAC) is a well-known surgical procedure in preclinical research. This method induces a pressure overload cardiac hypertrophic response in the left ventricle, which ...

Sydney's life sciences sector has reached a major milestone, with Kurraba Group announcing the first confirmed partners for ION – a purpose-built commercial life sciences precinct set to redefine ...

Targeting senescent cells with dasatinib-quercetin preserves disc structure and modulates degeneration-associated pathways in a mouse model. Intervertebral disc degeneration is a major cause of ...

A newly published review article highlights the critical role of fatty acid metabolism in shaping the tumor microenvironment and influencing cancer progression, offering fresh perspectives for the ...

Lens uses genomic language models to detect antibiotic resistance genes from DNA sequences, performing especially well on long-read data and on some ARGs poorly represented in reference databases.

A rapidly advancing area of biomedical innovation is shining a spotlight on miR-128-3p, a small yet powerful molecule with the potential to reshape how diseases—especially cancer—are detected, ...

Substantial and sustained weight-loss has been linked to a reduced risk of cancer and cancer-related death, mainly in women. Two new studies now provide clues to why the risk is reduced - and suggest ...

Food insecurity among adults in Tasmania was strongly associated with lower diet satisfaction and poorer self-rated mental and physical health, with diet dissatisfaction showing the strongest link.