Systematic and systemic both come from system. Systematic is the more common word; it most often describes something that is done according to a system or method. Systemic describes what relates …

SYSTEMIC definition: of or relating to a system, especially when affecting the entirety of a thing. See examples of systemic used in a sentence.

SYSTEMIC definition: 1. A systemic drug, disease, or poison reaches and has an effect on the whole of a body or a plant…. Learn more.

Definition of systemic adjective in Oxford Advanced Learner's Dictionary. Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and more.

Systemic refers to something that affects an entire system, like lack of transparency in a governing body. Systematic refers to an attribute of a process itself, specifically, that it is machine-like in its efficiency …

Systemic refers to something that is prevalent throughout or affecting the whole system or body. It can be used in various contexts like biology, medicine, sociology, or politics, indicating a widespread …

Jan 20, 2026 · Adjective systemic (not comparable) Embedded within and spread throughout and affecting a whole system, group, body, economy, market, or society.

systemic, adj. & n. meanings, etymology, pronunciation and more in the Oxford English Dictionary

Systemic definition: Of or relating to systems or a system.

The adjective systemic is often used to describe diseases or disorders; a systemic illness affects your whole body or an entire system — like your digestive system.